Extracellular serine protease

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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Details

C435S252330, C435S320100, C435S325000, C435S348000, C435S410000, C536S023200

Reexamination Certificate

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07732163

ABSTRACT:
The present invention provides a DNA encoding a novel extracellular serine protease termed Tumor Antigen Derived Gene-14 (TADG-14) which is overexpressed in ovarian, breast and colon carcinoma samples. Also provided are vector and host cells capable of expressing the DNA of the present invention, as well as the uses of the DNA and protein of the present invention. Also provided is a TADG-14 protein variant that has a potential role for detecting and targeting of ovarian carcinomas.

REFERENCES:
Mitsui et al, Eur J Biochem 260: 627-634, 1999.

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