Extracellular serine protease

Details Extracellular serine protease Extracellular serine protease

2006-03-21

2006-03-21

Bugaisky, Gabriele (Department: 1656)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S320100, C435S252300, C435S252330, C435S325000, C435S348000, C435S419000, C435S226000, C536S023500, C536S023200

Reexamination Certificate

active

07014993

ABSTRACT:
The present invention provides a DNA encoding a Tumor Antigen Derived Gene TADG-14 protein selected from the group consisting of: (a) isolated DNA which encodes a TADG-14 protein; (b) isolated DNA which hybridizes to isolated DNA of (a) above and which encodes a TADG-14 protein; and (c) isolated DNA differing from the isolated DNAs of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a TADG-14 protein. Also provided is a vector capable of expressing the DNA of the present invention adapted for expression in a recombinant cell and regulatory elements necessary for expression of the DNA in the cell.

REFERENCES:
Chen, Z.-L. et al.J. Neurosci.15(7)5088-5097 (1995).
Tanimoto, H. et al.Cancer Research57:2884-2887 (1997).
Bowie et al. Deciphering the message in protein sequecnes: tolerance to amino acid substitutions. Science 247: 1306-1310, Mar. 16, 1990.

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