Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1993-07-09
1994-08-30
Chan, Christina Y.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303891, 5303881, 53038885, 435 7021, C07K 1528, C12N 512
Patent
active
053429249
ABSTRACT:
Antigenic epitopes associated with the extracellular segment of the domain which anchors immunoglobulins to the B cell membrane are disclosed. For IgE, the epitopes are present on IgE-bearing B cells but not basophils or the secreted, soluble form of IgE. Three different isoforms of the C-terminal segment of the human .epsilon. chain resulting from alternative mRNA splicings in the membrane exon region are disclosed, one of which is secreted and not membrane-bound.
REFERENCES:
patent: 5254671 (1993-10-01), Chang
Peng et al., J. Immunol, 1992, 148:129 Goding et al., Monoclonal Antibodies, Principles & Practice, 1986 pp. 59-77.
Chan Christina Y.
Eisenchenk F. Christopher
Mirabel Eric P.
Tanox Biosystems, Inc.
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