Extracellular recording electrode

Chemistry: molecular biology and microbiology – Apparatus – Mutation or genetic engineering apparatus

Reexamination Certificate

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Details

C435S287100, C435S288300, C204S403010, C204S403030, C204S412000, C204S403130

Reexamination Certificate

active

07041492

ABSTRACT:
A multiple electrode includes a plurality of micro-electrodes provided on a substrate, and a wiring portion for providing an electrical signal to the micro-electrodes or extracting an electrical signal from the micro-electrodes. Each micro-electrode has porous conductive material on its surface, and the impedance of the micro-electrode is 50 kΩ or less. Preferably, the porous conductive material is gold, and formed by the passage of current at a current density of 1.0 to 5.0 A/dm2for 10 to 360 sec. The multiple electrode may include micro-electrodes provided on a substrate in the form of a matrix, a lead line connected to the micro-electrodes, and an electrical junction connected to an end of the lead line.

REFERENCES:
patent: 5143090 (1992-09-01), Dutcher et al.
patent: 5282844 (1994-02-01), Stokes et al.
patent: 5810725 (1998-09-01), Sugihara et al.
patent: 0 585 933 (1993-09-01), None
patent: 0 689 051 (1995-06-01), None
patent: 0769308 (1997-04-01), None
patent: 4-204244 (1992-07-01), None
patent: 06-078889 (1994-03-01), None
patent: 06-296595 (1994-10-01), None
patent: 2000-333921 (2000-12-01), None
patent: WO 99/34202 (1999-07-01), None
“Multichannel Cell Membrane Potential Measuring System and its Application to Cortical Development Study”, by Sugihara, et al., National Technical Report vol. 42, No. 2, Apr. 1996, pp. 112-119.
Copy of European Search Report dated Feb. 15, 2005.

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