Extra pure semi-synthetic blood substitute

Details Extra pure semi-synthetic blood substitute Extra pure semi-synthetic blood substitute

1987-11-10

1992-01-28

Kepplinger, Esther L.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530380, 530384, 530395, 530413, 530414, 530415, 530416, 530417, 530419, C07K 1514

Patent

active

050845586

ABSTRACT:
A blood substitute and plasma expander comprising a cross-linked, substantially endotoxin-free homoglobin solution and process for preparing same. The process comprises fractionating whole blood, separating out a stromal-free, sterile hemoglobin solution, chromatographically separating endotoxins from said hemoglobin solution and crosslinking the resulting endotoxin-free hemoglobin solution.

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