Drug – bio-affecting and body treating compositions – Topical sun or radiation screening – or tanning preparations
Patent
1993-08-27
1997-11-25
Wu, Shean C.
Drug, bio-affecting and body treating compositions
Topical sun or radiation screening, or tanning preparations
424 60, 424 62, 424 63, 514844, A61K 742, A61K 744, A61K 7135
Patent
active
056909144
ABSTRACT:
An external preparation for skin including one or more than two types of tranexamic acid derivatives represented by the following general formula (A). GENERAL FORMULA (A) ##STR1## (In the formula (A), R.sub.1, R.sub.2 and R.sub.3 represents hydrogen atoms or substituents and at least one of these is the substituent.) The external preparation for skin including the derivatives have excellent depigmentation effect as well as skin care effect.
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Journal of the American Chemical Society; vol. 74; 1952; pp. 676-678; The Preparation of Peptides Using Mixed Carbonic-carboxylic Acid Anhydrides; J. R. Vaughan, Jr., et al.
Journal of the American Chemical Society; vol. 86, No. 9, May 5, 1964; pp. 1839-1842; The Use of Esters of N-Hydroxysuccinimide in Peptide Synthesis; George W. Anderson, et al.
Journal of the American Chemical Society; vol. 89; 1967; pp. 5012-5017; A Reinvestigation of the Mixed Carbonic Anhydride Method of Peptide Synthesis; George W. Anderson, et al.
Akiyama Naoe
Kitamura Kenji
Morikawa Yoshihiro
Ohnuma Manami
Suetsugu Masaru
Shiseido Co., Ltd
Wu Shean C.
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