External dermatological composition

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424448, 424449, 424 81, A01R 970

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active

049389645

ABSTRACT:
An external dermatological composition containing a drug supply layer carried on a support and containing 5% to 35% by weight of ketoprofen in an acrylic or methacrylic copolymer, which copolymer is composed of (i) 0.5% to 11.0% by weight of an .alpha.,.beta.-unsaturated carboxylic acid or its anhydride, (ii) 0.1% to 28.0% by weight of a vinyl monomer, (iii) 1.0% to 5.5% by weight of a hydroxy C.sub.2 -C.sub.4 alkyl ester of acrylic or methacrylic acid, and (iv) a balance of a C.sub.4 -C.sub.18 alkyl ester of acrylic or methacrylic acid, and has a glass transition point of -15.degree. C. to -70.degree.C.

REFERENCES:
patent: 4740374 (1988-04-01), Nakano et al.
patent: 4765974 (1988-08-01), Tokuda et al.
patent: 4772470 (1988-09-01), Inoue et al.
Patent Abstracts of Japan, vol. 10, No. 128 (C-345)[2185], May 13, 1986, JPA-60252412, Nichiban K.K.
Life Sciences, vol. 39, No. 12 (1986) pp. 1043-1050.
Therapeutic Research, vol. 3, No. 6 (1985) pp. 1099-1116.

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