Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1992-06-15
1995-08-29
Krass, Frederick
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424457, 424458, 424459, 424460, 424461, 424462, 424468, 424474, 424475, 424494, 424497, 427 221, A61K 956, A61K 930
Patent
active
054458293
ABSTRACT:
An extended release pharmaceutical formulation adapted to approach zero order release of drug over a 12 to at least 24 hour period, comprised of a mixture of 0 to about 50% of an immediate release particle containing a drug, inert substrate and binder, coated with talc and up to 100% of an extended release particle comprising the immediate release particle coated with a dissolution modifying system containing plasticizers and a film forming agent.
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The Dow Chemical Company "Formulating for Controlled Release with METHOCEL Cellulose Ethers" (1987).
Garegnani James A.
Paradissis George N.
Whaley Roy S.
Harrison Robert H.
K-V Pharmaceutical Company
Krass Frederick
Nath Gary M.
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