Extended release gemfibrozil composition

Details Extended release gemfibrozil composition Extended release gemfibrozil composition

1989-02-02

1990-05-15

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424468, 424469, 424497, A61K 926

Patent

active

049256769

ABSTRACT:
A disintegratable gemfibrozil tablet providing both immediate and enteric release is compressed from a mixture of a first granulation of gemfibrozil with at least one acid-disintegratable binder and a second granulation formed from the first granulation but regranulated or coated with an alkali-disintegratable formulation of at least one substantially alkali-soluble and substantially acid-insoluble polymer.

REFERENCES:
patent: 4132753 (1979-01-01), Blichare et al.
patent: 4195084 (1980-03-01), Ong
patent: 4263272 (1981-04-01), Frigerio
patent: 4291016 (1981-09-01), Nougaret
patent: 4533562 (1985-08-01), Ikegami et al.
patent: 4661162 (1987-04-01), Kurihara et al.
patent: 4716033 (1987-12-01), Denick, Jr.
patent: 4778676 (1988-10-01), Yang et al.
patent: 4814354 (1989-03-01), Ghebre-Sellassie et al.
patent: 4816264 (1989-03-01), Phillips et al.

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