Extended release composition containing Tramadol

Details Extended release composition containing Tramadol Extended release composition containing Tramadol

2002-04-11

2010-12-28

Channavajjala, Lakshmi S (Department: 1611)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

C424S451000, C424S458000, C424S459000, C424S464000, C424S489000

Reexamination Certificate

active

07858118

ABSTRACT:
An oral Tramadol-containing pharmaceutical composition suitable for once daily administration, which contains an amount of Tramadol or a pharmaceutically acceptable salt thereof, providing in vivo, a time of Tramadol peak plasma concentration (Tmax) of greater than 10 hours, and peak Tramadol plasma concentration (Cmax) which are less than three times the plasma concentration obtained 24 hours after administration (C24h) of a single dose of the composition.

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