Extended cycle multiphasic oral contraceptive method

Details Extended cycle multiphasic oral contraceptive method Extended cycle multiphasic oral contraceptive method

2005-03-14

2009-08-04

Badio, Barbara P (Department: 1612)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

Reexamination Certificate

active

07569560

ABSTRACT:
A multiphasic method of contraception provides for sequentially administering to a female of child bearing age: (a) a Phase I composition containing a progestogen and an estrogen for about 4 to about 7 days; (b) a Phase II composition containing a progestogen and an estrogen for about 8 to about 16 days; (c) a Phase III composition containing a progestogen and an estrogen for about 4 to about 7 days; and (d) optionally, a Phase IV composition which is a placebo or a non-steroidal component, wherein the ethinyl estradiol equivalent amount of estrogen in the Phase II composition is at least 5 mcg greater than the ethinyl estradiol equivalent amount of estrogen in each of the Phase I and III compositions. Preferably the sequential administration is repeated the day following the completion of the administration of the Phase III compositions providing an extended cycle multiphasic oral contraceptive method.

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patent: WO98/04268 (1998-02-01), None
Edwards, L.A. “An Update on Oral Contraceptive Options”, Formulary 2004 United States, vol. 39, No. 2, Feb. 2004 pp. 104-121.
Hamerlynck J.V. Th et al. “Postponement of Withdrawal Bleeding in Women Using Low-Dose Combined Oral Contraceptives” Contraception, Geron-X, Inc., Los Altos, Ca, US, vol. 35, No. 3, 1987 pp. 199-206.

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