Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing
Patent
1995-07-11
1999-09-21
Wax, Robert A.
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
435189, 435212, 530350, A61K 3843, C12N 902, C12N 948, C07K 100
Patent
active
059550724
ABSTRACT:
The present invention provides expression systems for exogenous polypeptides wherein the polypeptide is expressed as a fusion protein together with clover yellow virus Nuclear Inclusion a (NIa), the NIa component serving to autolyze the fusion protein after expression. This system can be used to express a novel polypeptide which we have designated KM31-7 protein and which is capable of reducing dichloroindophenol and reduced glutathione. This polypeptide is useful in the treatment of disorders caused by oxidative stress.
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Kawashima Ichiro
Koishi Ryuta
Serizawa Nobufusa
Takahashi Tohru
Hobbs Lisa J.
Sankyo Company Limited
Wax Robert A.
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