Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2003-11-12
2009-06-23
Vogel, Nancy (Department: 1636)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S007100, C424S191100, C530S350000
Reexamination Certificate
active
07550275
ABSTRACT:
In this application is described the expression and purification of a recombinantPlasmodium falciparum(3D7) LSA-NRC polypeptide. The method of the present invention produces a highly purified polypeptide which is useful as a vaccine and as a diagnostic reagent.
REFERENCES:
patent: 6319502 (2001-11-01), Guerin-Marchand et al.
Phillips, Clinical Microbiol. Rev., Jan. 2001, vol. 14, No. 1, pp. 208-226.
Giles, “Why don't we have a malaria vaccine?”, http://malaria.wellcome.ac.uk/doc, Wellcome Trust malaria website, Feb. 17, 2007.
Londono et al., J. Immunol., vol. 145, pp. 1557-1563, Sep. 1, 1990.
Druilhe et al., PLoS Medicine, 2, 11, 1135-1145, 2005.
Fidock et al., 1994. Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T cell determinants. J. Immunol. 153, 190-204.
Doolan et al., 2000. The complexity of protective immunity against liver-stage malaria. J. Immunol. 165, 1453-1462.
Connelly et al., 1997. T-Cell immunity to peptide epitopes of liver-stage antigen 1 in an area of Papua New Guinea in which malaria is holoendemic. Infect. Immunity 65, 5082-5087.
Krzych et al., 1995. T lymphocytes from volunteers immunized with irradiated Plasmodium falciparum sporozoites recognized liver and blood stage malaria antigens. J. Immunol. 155, 4072-4077.
Angov Evelina
Barbosa Arnoldo
Hillier Collette J.
Kumar Sanjai
Lanar David E.
Arwine Elizabeth
The United States of America as represented by the Secretary of
Vogel Nancy
LandOfFree
Expression, purification and uses of a Plasmodium... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Expression, purification and uses of a Plasmodium..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Expression, purification and uses of a Plasmodium... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4082968