Expression of the recombinant tumor necrosis factor binding prot

Details Expression of the recombinant tumor necrosis factor binding prot Expression of the recombinant tumor necrosis factor binding prot

1993-09-24

1998-09-22

Walsh, Stephen

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 701, 4353201, 435325, 435358, 435366, 530350, C12P 2106

Patent

active

058112618

ABSTRACT:
Tumor Necrosis Factor Binding Protein I (TBP-I), precursors and analogs thereof, are produced by transfecting eukaryotic cells with an expression vector comprising al DNA molecule encoding the whole human type I TNF receptor or a soluble domain thereof, and culturing the transfected cells, whereby the soluble proteins are secreted into the medium.

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