Expression of recombinant polypeptides with improved purificatio

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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435 697, 4352523, 4353201, 530369, 536 234, C07K 1300

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active

053229304

ABSTRACT:
An improved method for expressing peptides as fusion proteins, uses a carrier for a heterologous peptide to provide a fusion protein having a high pI. The high isoelectric point facilitates separation of the fusion protein from all other host cell proteins, and separation of the carrier from the peptide after cleavage.

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Sassenfeld et al., Bio/Technology (Jan. 1984) pp. 76-81.

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