Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1992-05-20
1995-10-24
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 696, 435219, 435226, 4352523, 4353201, 935 28, 935 32, 935 69, 935 70, 935 71, 935 60, G12N 1500, G12N 1557, G12N 1581, G12N 1585
Patent
active
054609500
ABSTRACT:
Compositions and methods are provided for endopeptidase production and for enhanced efficiencies of processing heterologous precursor polypeptides to mature polypeptides, including proteins requiring gamma-carboxylation for biological activity. These compositions and methods utilize recombinant PACE, a mammalian endopeptidase that is specific for dibasic amino acid sites.
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Barr Philip J.
Brake Anthony J.
Kaufman Randal J.
Tekamp-Olson Patricia
Wasley Louise
Chiron Corporation
Genetics Institute Inc.
Moore William W.
Wax Robert A.
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