Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-06-07
1999-11-16
Achutamurthy, Ponnathapura
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 691, 435219, 435226, 4352523, 4353201, 435471, 536 235, C12N 1557, C12N 1579, C12N 1585, C12N 964
Patent
active
059860790
ABSTRACT:
Compositions and methods are provided for endopeptidase production and for enhanced efficiencies of processing heterologous precursor polypeptides to mature polypeptides, including proteins requiring gamma-carboxylation for biological activity. These compositions and methods utilize recombinant PACE, a mammalian endopeptidase that is specific for dibasic amino acid sites.
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I.
Barr Philip J.
Brake Anthony J.
Kaufman Randal J.
Tekamp-Olson Patricia
Wasley Louise
Achutamurthy Ponnathapura
Chiron Corporation
Genetics Institute Inc.
Moore William W.
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