Expression of human SOD in blue green algae

Details Expression of human SOD in blue green algae Expression of human SOD in blue green algae

1995-01-03

1998-09-08

Jones, W. Gary

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 4352523, 4353201, 435946, 536 232, 536 241, 935 6, 935 29, 935 41, 935 56, C12P 2100, C12N 1570, C12N 1563, C07H 2102

Patent

active

058044086

ABSTRACT:
A method for expressing a physiologically active polypeptide in cells of a blue-green alga by transforming the cells of a blue-green alga with a recombinant DNA containing a structural gene encoding the polypeptide, characterized in that as the recombinant DNA is used a recombinant DNA which contains a structural gene encoding the physiologically active polypeptide, the transcription initiation region of the RuBisCO gene of Anacystis nidulans located upstream of the structural gene, and the transcription termination region of the RuBisCO gene located downstream of the structural gene. According to this method, physiologically active polypeptide can efficiently be expressed using blue-green algae.

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