Expression of human serum albumin in plastids

Details Expression of human serum albumin in plastids Expression of human serum albumin in plastids

2006-04-18

2010-06-22

Kubelik, Anne (Department: 1638)

Multicellular living organisms and unmodified parts thereof and

Plant, seedling, plant seed, or plant part, per se

Higher plant, seedling, plant seed, or plant part

C435S320100, C426S655000

Reexamination Certificate

active

07741536

ABSTRACT:
Humans Serum Albumin (HSA) or an HSA fusion protein is expressed in plant plastids. A plastid transformation vector is made which contains an expression cassette that contains regulatory sequences, the coding region for HSA or an HSA fusion protein and a selectable marker coding sequence. The vector is used to transform a plant where the plant expresses the HSA or HSA fusion protein. HSA is isolated and purified from the plant. A preferred plant is tobacco.

REFERENCES:
patent: 4616078 (1986-10-01), DiMarchi
patent: 4956282 (1990-09-01), Goodman et al.
patent: 4963665 (1990-10-01), Rotwein et al.
patent: 5545817 (1996-08-01), McBride et al.
patent: 5650307 (1997-07-01), Sijmons et al.
patent: 5877402 (1999-03-01), Maliga et al.
patent: 6004782 (1999-12-01), Daniell et al.
patent: 7294506 (2007-11-01), Daniell et al.
patent: 2002/0174453 (2002-11-01), Daniell et al.
patent: WO 99/10513 (1999-03-01), None
patent: WO 99/18225 (1999-04-01), None
patent: WO 00/03012 (2000-01-01), None
Gadanii et al, Agro Food Industry Hi-Tech, (1995) vol. 6, No. 2, pp. 3-6.
Sijmons, P. C. et al. “Production of Correctly Processed Human Serum Albumin in Transgenic Plants”,Biotechnology, Mar. 1990, pp. 217-221, vol. 8.
Boston, R. S. et al. “Molecular Chaperones and Protein Folding in Plants”,Plant Molecular Biology, 1996, pp. 191-222, vol. 32.
Crickmore, N. et al. “Revision of the Nomenclature for theBacillus thuringiensisPesticidal Crystal Proteins”,Microbiology and Molecular Biology Reviews, Sep. 1998, pp. 807-813, vol. 62.
Kota, M. et al. “Overexpression ofBacillus thuringiensis(Bt) Cry2Aa2 Protein in Chloroplast Confers Resistance to Plants Against Susceptible and Bt-resistant Insects”Proc. Natl. Acad. Sci. USA, Mar. 1999, pp. 1840-1845, vol. 96.
Heifetz, P. B. “Genetic Engineering of the Chloroplast”,Biochimie, 2000, pp. 655-666, vol. 82.
Kanno, A. et al. “A Transcription Map of the Chloroplast Genome from Rice (Oryza sativa)”,Curr Genet., Feb. 1993, pp. 166-174, vol. 23, No. 2.
McBride, K.E. et al. “Amplification of a ChimericBacillusGene in Chloroplasts Leads to an Extraordinary Level of an insecticidal Protein in Tobacco”,Biotechnology, Apr. 1995, pp. 362-365, vol. 13.
Zoubenko, O. V. et al. “Efficient Targeting of Foreign Genes into the Tobacco Plastid Genome”,Nucleic Acid Research, 1994, pp. 3819-1824, vol. 22, No. 19.
Daniell, H. et al. “Containment of Herbicide Resistance Through Genetic Engineering of the Chloroplast Genome”,Nature Biotechnology, 1998, pp. 345-348, vol. 16.
Lu, Z. et al. “Characterization of Republication Origins Flanking the 23S rRNA Gene in Tobacco Chloroplast DNA”,Plant Mol. Biol., 1996, pp. 693-706, vol. 32.
Staub, J.M. et al, “Long regions of homologous DNA are incorporated into the tobacco plastid genome by transformation.Plant Cell”, Jan. 1992, pp. 39-45, vol. 4, No. 1.
Datta, R. et al., “Transformation of the Tobacco Chloroplast Genome with the aroA Gene to Confer Glyphosate Tolerance,”Supplement to Plant Physiology, Jun. 1996, p. 168, vol. 111, No. 2.

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