Expression of human protein C in mammary tissue of transgenic ma

Multicellular living organisms and unmodified parts thereof and – Nonhuman animal

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435 696, 435212, C12N 500, C12N 1500, C12N 948, C12P 2104

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active

055896049

ABSTRACT:
Recombinant protein C characterized by a high percentage of active protein can be obtained in the milk of transgenic mammals that incorporate DNAs according to the present invention. Transgenic mammals of the present invention are produced by introducing into developing embryos DNA that encodes protein C, such that the DNA is stably incorporated in the DNA of germ line cells of the mature mammals and inherited in normal, mendelian fashion.

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