Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...
Patent
1991-12-02
1993-10-26
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
435974, 930221, 935 33, 935 38, 935 40, 935 47, 935 73, C12N 900, C12N 1549
Patent
active
052565548
ABSTRACT:
This invention describes pHRT25, a plasmid containing a modified pol gene of the Human Immunodeficiency Virus Type 1 (HIV-1), formerly HTLV-III, under control of an inducible trp promoter. Methods of expressing reverse transcriptase activity using pHRT25 in E. coli are described.
REFERENCES:
patent: 4387162 (1983-06-01), Aigle et al.
patent: 4487835 (1984-12-01), Uhlin et al.
patent: 4663290 (1987-05-01), Weis et al.
N. Tanese et al. (1988) DNA 7(6):407-416.
C. H. Schein et al. (1988) Bio/Technology 6:291-294.
H. F. Seow et al. (1989) Bio/Technology I:363-368.
A. D. Hoffman et al. (1985) Virology 147:326-335.
Tacon, W. et al., Molec. Gen. Genet., vol. 177, pp. 427-438, 1980.
Tanese, N. et al., Proc. Natl. Acad. Sci., vol. 82, pp. 4944-4948, Aug., 1985.
Chang, N. et al., Science, vol. 228, pp. 93-96, Apr., 1985.
Ratner, L. et al., Nature, vol. 313, pp. 277-284, Jan., 1985.
Wain-Hobson, et al., Cell, vol. 40, pp. 9-17, Jan. 1985.
Muesing, M. et al., Nature, vol. 313, pp. 450-458, Feb., 1985.
Farmerie, W. et al., Science, vol. 236, pp. 305-308, Apr., 1987.
Tanese, N. et al., J. Virology, vol. 59, pp. 743-745, Sep., 1986.
Goff Stephen P.
Haseltine William A.
Tanese Naoko
Railey II Johnny F.
Schwartz Richard A.
The Dana Farber Cancer Institute
The Trustees of Columbia University in the City of New York
White John P.
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