Expression of higher eucaryotic genes in aspergillus

Details Expression of higher eucaryotic genes in aspergillus Expression of higher eucaryotic genes in aspergillus

1987-01-09

1990-06-19

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 696, 435171, 4351723, 435212, 435254, 435320, 435 913, 435917, 530351, 530387, 536 27, 935 6, 935 10, 935 24, 935 34, 935 36, 935 48, 935 60, 935 68, C12P 2100, C12N 1500, C12N 114, C07H 1512

Patent

active

049353497

ABSTRACT:
A method for expressing higher eucaryotic genes in Aspergillus through the use of a recombinant plasmid capable of integration into the chromosomal DNA of Aspergillus is disclosed. It is preferred to utilize a transcriptional promoter within a DNA construct contained in the plasmid that is of a DNA sequence encoding an ADH enzyme or a TPI enzyme. Promoters capable of directing the expression of a heterologous gene in Aspergillus, as well as other filamentous fungal genera are also disclosed.

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