Expression of heterologous genes from an IRES translational...

Chemistry: molecular biology and microbiology – Vector – per se

Reexamination Certificate

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Reexamination Certificate

active

07056730

ABSTRACT:
The present invention relates to a retroviral vector which expresses a gene, e.g. for therapeutic use and/or of viral origin, under the translational control of an internal ribosomal entry site (IRES) resulting in the efficient translation of said gene.

REFERENCES:
patent: 5925565 (1999-07-01), Berlioz et al.
patent: 6410313 (2002-06-01), Kasahara et al.
patent: WO 93/03143 (1993-02-01), None
Murakami et al., Gene, 202: 23-29 (1997).
Jespersen et al., Gene, vol. 293 (2), pp. 227-235 (1999).

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