Expression of hepatitis B S and preS.sub.2 proteins in Pichia pa

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4351723, 43525423, 4353201, C12N 119, C12N 1551, C12N 1581

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active

056502966

ABSTRACT:
A process for the enhanced production of antigenic particles consisting essentially of hepatitis B S protein and preS.sub.2 protein. Also disclosed are novel DNA molecules and hosts transformed with these molecules.

REFERENCES:
patent: 4816564 (1989-03-01), Ellis et al.
patent: 4895800 (1990-01-01), Tschopp et al.
Cregg et al. Bio chnology 5:479-485 (1987).
Wood et al. Nature 314:446-449 (1985).

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