Expression of hepatitis B S and preS.sub.2 proteins in methylotr

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...

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530350, 435 693, 4351723, 4352542, 43525423, 4353201, 4241891, C07K 1410, C12N 1581

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active

056706308

ABSTRACT:
A process for the enhanced production of antigenic particles consisting essentially of hepatitis B S protein and preS.sub.2 protein. Also disclosed are novel DNA molecules and hosts transformed with these molecules.

REFERENCES:
patent: 4816564 (1989-03-01), Ellis et al.
patent: 4895800 (1990-01-01), Tschopp et al.
Cregg et al. Biotechnology 5:479-485 (1987).
Wood et al. Nature 314:446-449 (1985).

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