Expression of fusion protein of HIV envelope and HBsAg

Details Expression of fusion protein of HIV envelope and HBsAg Expression of fusion protein of HIV envelope and HBsAg

1989-09-19

1992-07-14

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4351723, 435 691, 435 693, 4353201, 435255, 536 27, 935 10, 935 22, C12N 506, C12N 519, C12P 2106, C07H 2104

Patent

active

051302489

ABSTRACT:
The present invention relates to recombinant fusion polypeptides of HIV envelope and HBsAg, suitable as vaccines against AIDS and/or ARC and hepatitis, as well as immunogens for inducing antibodies for passive protection or treatment of AIDS and/or ARC.

REFERENCES:
S. Matsushita et al. (1988) Journal of Virology 62:2107-2114.
D. M. Barnes (1988) Science 240:719-721.
M. R. Hilleman (1988) Vaccine 6:175-179.
K. Javaherian et al. (1989) Proc. Natl. Acad. Sci. USA 86:6768-6772.
C. Gurgo et al. (1988) Virology 164:531-536.
T. J. Palker et al. (1988) Proc. Natl. Acad. Sci. USA 85:1932-1936.
J. R. Rusche et al. (1988) Proc. Natl. Acad. Sci. USA 85:3198-3202.
T. J. Palker et al. (1989) Journal of Immunology 142:3612-3619.
Ratner, L. et al., "Human T-Lymphotropic Retroviruses," in O'Brien, S. J. (ed). Genetic Maps 1987 Cold Spring Harbor 1987, pp. 124-129.
Franchini, G. et al. Nature 328, 539 (1987).
Varmus, H. Genes & Dev. 2, 1055 (1988).
Goudsmit, J. et al., Proc. Nat. Acad. Sci. 85, 4478 (1988).
Ho. D. D. et al., J. Virol. 61, 2024 (1987).
Palker, T. J. et al., Proc. Natl. Acad. Sci. 85, 1932 (1988).
Skinner, M. A. et al., J. Virol. 62, 4195 (1988).
Berman, P. W. et al., Proc. Natl. Acad. Sci. 85, 5200 (1988).
Hu, S. L. et al., Nature 328, 721 (1987).
Lasky, L. A. et al., Science 233, 209 (1986).
Putney, S. et al., Science 234, 1392 (1986).
Robey, W. G. et al., Proc. Natl. Acad. Sci. 83, 7023.
Rusche, J. R. et al., Proc. Natl. Acad. Sci. 84, 6924 (1987) (Rusche II).
Genetic Engineering News, Jan. 1988, vol. 8, p. 23.
Hruska, J. F. et al., J. Virol. 21, 666 (1977).
Valenzuela, P. et al., 3 (4), 317 (1985).
Zoller, M. J. et al., Nucl. Acids. Res. 10, 6487 (1982).
Russell, D. W. et al., J. Biol. Chem., 258, 2674 (1983).
Kniskern, P. J. et al., Gene 46, 135 (1986) (Kniskern I).
Ellis, R. W. et al., Viral Hepatitis and Liver Disease, Alan R. Liss, Inc., pp. 1079-1086, 1988.
Carty, C. et al., J. Ind. Microbio. 2, 117 (1987).
Kniskern, P. et al., Hepatology 8, 82 (1988) (Kniskern II).
Wampler, D. E. et al., in Chanock, R. M. et al. (eds.) "Modern Approaches to Vaccines," Cold Spring Harbor 1984, pp. 251-256.
Robertson, G. A. et al., J. Virol. Meth. 20, 195 (1988).
Michel, M-L. et al., Proc. Natl. Acad. Sci. 85, 7957 (1988).
Adams, S. E. et al., Nature 329, 68 (1987).
Neurath, A. R. et al. Molecular Imm. 26, 53 (1989).
Delpeyroux, F. et al., J. Mol. Biol. 195, 343 (1987).
Standring, D. N. et al., Proc. Natl. Acad. Sci. 83, 9338 (1986).
Ono, Y. et al., Nucl. Acads. Res. 11, 1747 (1983).
Fujiyama, A. et al. Nucl. Acids Res. 11, 4601 (1983).

Affiliated with

Also associated with

Rating

Expression of fusion protein of HIV envelope and HBsAg does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Expression of fusion protein of HIV envelope and HBsAg, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Expression of fusion protein of HIV envelope and HBsAg will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-334212