Expression inhibitor comprising an antisense oligonucleotide der

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435375, 435455, 536 231, C12N 1500, C12N 1509, C12N 1511

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active

058471030

ABSTRACT:
There is provided an inhibitor of expression of human IL-6R, whose effective component is an antisense oligonucleotide derivative which hybridizes to the region of a nucleotide sequence of 9 to 30 nucleotides including the translation initiation codon of mRNA coding for human interleukin-6 receptor (IL-6R).

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Chemistry; vol. 46, No. 10, pp. 681 to 684 (Kagaku Dojin (Kyoto)) Oct. 1989 (10. 1989), Akira Murakami, "Antisense DNA method".

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