Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-09-29
2011-11-22
Bristol, Lynn (Department: 1643)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S252330, C435S320100
Reexamination Certificate
active
08062865
ABSTRACT:
The present invention provides a dicistronic message for producing an antibody molecule, in which the upstream cistron contains DNA coding for the light chain of the antibody and the downstream cistron contains DNA coding for the corresponding heavy chain, characterised in that the dicistronic message comprises a sequence selected from AEOS1 (SEQ ID NO:1), AEOS2 (SEQ ID NO:2), AEOS3 (SEQ ID NO:3), AEOS4 (SEQ ID NO: 4), AEOS5 (SEQ ID NO:5), AEOS6 (SEQ ID NO:6), AEOS7 (SEQ ID NO:7), AEOS8 (SEQ ID NO:8), AEOS9 (SEQ ID NO:9), AEOS1O (SEQ ID NO:10) and AEOS11 (SEQ ID NO:11).
REFERENCES:
patent: 6468738 (2002-10-01), Kang
patent: 7419659 (2008-09-01), Popplewell
patent: 7452976 (2008-11-01), Popplewell et al.
patent: 01/94585 (2001-12-01), None
patent: 03/048208 (2003-06-01), None
Ellis Mark
Humphreys David Paul
Bristol Lynn
McDonnell Boehnen & Hulbert & Berghoff LLP
UCB Pharma S.A.
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