Expression and use of human fibroblast growth factor receptor

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.

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C07K 1300

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active

052295010

ABSTRACT:
A new receptor for fibroblast growth factor has been cloned and expressed. The recombinant receptor is useful for inhibiting FGF activity, and for screening compounds for binding activity similar to that of FGF. A soluble, truncated recombinant receptor is also prepared, and is capable of binding FGF.

REFERENCES:
Kiefer et al 1991 Growth Factors 5:115-127.
Isacchi et al 1990 Nuc. Acids Res. 18:1906.

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