Expression and purification of ATM protein using vaccinia virus

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S069100, C435S320100, C435S372000, C435S367000, C435S456000, C435S183000, C424S009340, C424S093210, C424S199100, C530S350000

Reexamination Certificate

active

06994975

ABSTRACT:
The present disclosure concerns methods for recombinantly producing functional ataxia-telangiectasia (ATM) protein, methods for isolating recombinant functional ATM protein, and uses of ATM protein. In particular, a method is disclosed for using a vaccinia virus vector to express ATM, and using immunoprecipitation or affinity tagging to isolate recombinant ATM.

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