Expansion of hematopoietic cells using midkine or pleiotrophin

Details Expansion of hematopoietic cells using midkine or pleiotrophin Expansion of hematopoietic cells using midkine or pleiotrophin

2005-09-06

2005-09-06

Kemmerer, Elizabeth (Department: 1647)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

C435S325000, C435S375000, C435S377000, C530S350000, C530S351000, C530S399000

Reexamination Certificate

active

06939669

ABSTRACT:
The present invention provides novel use of the MK family that is used alone as an agent for proliferating hematopoietic stem cells and hematopoietic precursor cells. The invention also provides an agent for remarkably enhancing the above-described effect for promoting the proliferation of hematopoietic stem cells and hematopoietic precursor cells, comprising the MK family in combination with known hematopoietic factors such as IL-3, IL-6, G-CSF, GM-CSF, M-CSF, SCF, and EPO.

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