Expandable member formed of a fibrous matrix for...

Details Expandable member formed of a fibrous matrix for... Expandable member formed of a fibrous matrix for...

2008-09-26

2011-12-13

Lucchesi, Nicholas D (Department: 3763)

Surgery

Means and methods for collecting body fluids or waste material

Absorbent pad for external or internal application and...

C604S096010, C604S103080, C604S286000

Reexamination Certificate

active

08076529

ABSTRACT:
An intraluminal catheter device having an expandable member formed of a matrix of fiber elements with a therapeutic agent incorporated therein. The therapeutic agent can be coated on the fiber elements in a co-axial configuration. The fiber elements may also have a second coating including a protective substance surrounding the therapeutic agent. The matrix of fiber elements can be formed by electrospinning. A process of delivering a therapeutic agent to a target site includes providing an intraluminal catheter device having an expandable member formed of a matrix of fiber elements, the expandable member having a therapeutic agent dispersed therein, and advancing the catheter device at a desired treatment site. Once at the desired treatment site, fluid is introduced into the inflation lumen to expand the expandable member from a first profile to a second profile, and the therapeutic agent is delivered to the desired treatment site.

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