Expandable biodegradable polymeric stents for combined...

Details Expandable biodegradable polymeric stents for combined... Expandable biodegradable polymeric stents for combined...

2006-10-31

2006-10-31

Woo, Julian W. (Department: 3731)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Arterial prosthesis

Stent structure

C623S001220, C623S001380, C623S001420

Reexamination Certificate

active

07128755

ABSTRACT:
An expandable biodegradable polymeric stent is fabricated with biodegradable polymer fibers (Poly-L-lactic acid, PLLA) in a coil shape that is constructed with both central and external or internal peripheral lobes. It is delivered and expanded using a conventional angioplasty balloon system. The disclosed stent can serve as a temporary scaffold for coronary vessels after PTCA or for peripheral endovascular stenting, or it can provide mechanical palliation for strictures of ductile organs (trachea, esophagus, bile and pancreatic ducts, ureter etc.). The disclosed stent also serves as a unique device for specific local drug delivery. Therapeutic agents (chemical compounds, protein enzyme and DNA sequences) and cells can be loaded into the stent and gradually released to target tissues. Local radiation therapy can also be delivered by a specially adapted stent.

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http://www.turmeric-curcumin.com/main.html.
Circulation, vol. 102, pp. 399-404, Feb. 15, 2000.

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