Exocrine gland tight junction-constituting protein jeap family

Details Exocrine gland tight junction-constituting protein jeap family Exocrine gland tight junction-constituting protein jeap family

2006-10-31

2006-10-31

Wax, Robert A. (Department: 1653)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S320100, C435S252300, C435S254110, C435S325000, C536S023500

Reexamination Certificate

active

07129063

ABSTRACT:
A mouse cDNA library from gene fragments encoding proteins localizing at cell-cell junctions was screened by a technique visualizing localization of a protein to to identify a junction-enriched and -associated protein, JEAP. GenBank homology search was performed based on the sequence. Based on the obtained sequence, a mouse cDNA library was screened to identify JEAP-2. By using prepared antibodies against these proteins, it was revealed that these proteins express specifically at tight junctions, in particular, tight junctions in exocrine glands.

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