Exo-3',4'-O-benzylidene-3"-demethylchartreusin and its salts

Details Exo-3',4'-O-benzylidene-3"-demethylchartreusin and its salts Exo-3',4'-O-benzylidene-3"-demethylchartreusin and its salts

1990-01-29

1992-09-22

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 181, 536 172, 536 41, C07H 1704, C07H 1524, A61K 3171

Patent

active

051497930

ABSTRACT:
Exo-3',4'-O-benzylidene-3"-dimethylchartreusin (exo-BDMC) or its salts and 3"-demethylchartreusin (3"-DMC) or its salts are provided according to the present invention. Exo-BDMC and its salts are useful for antitumorous agents and antibacterial agents. 3"-DMC and its salts are useful as starting materials for producing exo-BDMC.

REFERENCES:
patent: 4518589 (1985-05-01), Konishi et al.
patent: 4760136 (1988-07-01), Mori et al.
patent: 4927919 (1990-05-01), Yamada et al.
Konishi et al., The Journal of Antibiotics, vol. XXXIX (6), 784-791 (1986).
J-Patrick McGovren et al., Cancer Research, 37, 1666-1672 (1977).
Takai et al., J. Med. Chem., 23, 549-553 (1980).
Leach, B. E., et al., (1953) [J. Am. Chem. Soc., 75 4011-4012 (1953)].

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