Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-10-24
2006-10-24
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S307000, C514S355000, C544S176000, C546S146000, C546S298000, C548S317100
Reexamination Certificate
active
07125871
ABSTRACT:
Compounds of the formula (I) in which R1, R2and X1have the meanings given in the specification, modulate metabotropic glutamate receptor function and are useful in treating disorders of the central nervous system
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patent: WO 01/92213 (2001-12-01), None
Pellicciari et al. “Synthesis and Pharmacological Characterization of All Sixteen Stereoisomers of 2-(2′-Carboxy-3′-phenylcyclopropyl)glycine. Focus on (2S,1′S,2′S,3′R)-2-(2′-Carboxy-3′-phenylcyclopropyl)glycine, a Novel and Selective Group II Metabotropic Glutamate Receptors Antagonist” J. Med. Chem. 1996, vol. 39, pp. 2259-2269.
Pellicciari et al: “Synthesis and Pharmacological Characterization of All Sixteen Stereoisomers of 2-(2′-Carboxy-3′-phenylcyclopropyl)glycine. Focus on (2S.1′S.2′S.3′R)-2-(2′-Carboxy-3′-phenylcy clopropyl)glycine. a Novel and Selective Group II Metabotropic Glutamate Receptor Antagonist” Journal of Medicinal Chemistry. American Chemical Society. Washington. US. vol. 39. No. 11. 1996. pp. 2259-2269, XP002122695 ISSN: 0022-2623 cited in the application pp. 2259-2269.
Cano Ivan Collado
Ezquerra-Carrera Jesus
Marcos Liorente Alicia
Martin-Cabrejas Luisa Maria
Monn James Allen
Anderson Arvie J.
Kosack Joseph R.
Saeed Kamal A.
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