Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-05-13
1999-09-28
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5483011, 558 70, 558432, 560 48, 560119, 562457, 562501, A61K 31415, C07D23502
Patent
active
059589604
ABSTRACT:
Compounds of the formula ##STR1## in which R.sup.1 and R.sup.2 are as defined in the specification, and non-toxic metabolically labile ester and amides thereof are useful as modulators of metabotropic glutamate receptor function.
REFERENCES:
patent: 5661184 (1997-08-01), Helton et al.
patent: 5726320 (1998-03-01), Robey
patent: 5750566 (1998-05-01), Monn et al.
James A. Monn et. al., J. Med. Chem., 1997, 40, 528-537.
K. Shimamoto and Y. Ohfune, J. Med. Chem., 1996, 39, 407-423.
Yasufumi Ohfune et al., Bioorganic and Medicinal Chemistry Letters, vol. 3, No. 1, 15-18, 1993.
Haruhiko Shinozaki, Eur. Neurol 1994; 34 (suppl 3):2-9.
Roberto Pellicciari et al., J. Med. Chem., 1996, 39, 2259-2269.
T. Saitoh et al., British Journal of Pharmacology (1998) 123, 771-779.
Massey Steven Marc
Monn James Allen
Valli Matthew John
Eli Lilly and Company
Gaylo Paul J.
Hay Martin A.
Ramsuer Robert W.
Sackey Ebenezer
LandOfFree
Excitatory amino acid receptor modulators does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Excitatory amino acid receptor modulators, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Excitatory amino acid receptor modulators will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-703834