Excitatory amino acid receptor modulators

Details Excitatory amino acid receptor modulators Excitatory amino acid receptor modulators

1999-05-28

2000-12-12

McKane, Joseph

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514519, 514561, 558432, 560 48, 560119, 562400, 562457, 562501, A61K 3121, C07C25528, C07C 6974, C07C 6108

Patent

active

061600091

ABSTRACT:
Compounds of the formula ##STR1## in which R.sup.1 and R.sup.2 are as defined in the specification, and non-toxic metabolically labile ester and amides thereof are useful as modulators of metabotropic glutamate receptor function.

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James A. Moon et. al., J. Med. Chem., 1997, 40, 528-537.
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Roberto Pellicciari et al., J. Med. Chem., 1996, 39, 2259-2269.
T. Saitoh et al., British Journal of Pharmacology (1998) 123, 771-779.

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