Examination method of buffer capacity of saliva and...

Chemistry: analytical and immunological testing – Including titration or ph determination

Reexamination Certificate

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C436S162000, C436S164000, C436S169000

Reexamination Certificate

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10241645

ABSTRACT:
To provide a simple examination method of buffer capacity of saliva without influence by examiner's subjectivity and an examination instrument to carry out suitably the examination method, an examination instrument, in which two to ten kinds of chemical liquids each containing a pH indicator having a transition interval within a pH range of 3.0 to 7.0 and capable of easily discriminating its indicated color at two or more stages and an acid in an amount so as to exhibit a different pH value within a pH range of 1.5 or more but lower than 3.0 when water in the same amount as that of saliva to be examined is added at a temperature of 25° C. and a humidity of 50% are each immersed in a water-absorptive material, or are in a liquid or gel state and are accommodated within a constant-volume container, is prepared; saliva of a subject in a volume to be examined is added to each of the chemical liquids; after lapsing a predetermined time, the color of each chemical liquid is measured as a readily discriminable indicated color; and the buffer capacity of saliva is determined by overall evaluation from the readily discriminable indicated color as exhibited by the chemical liquid.

REFERENCES:
patent: 6762058 (2004-07-01), Takagi et al.
patent: 357175129 (1982-10-01), None
patent: 02002323493 (2002-11-01), None
patent: 02003083961 (2003-03-01), None
G. Frostell, Swedish Dental Journal, vol. 4, No. 3, pp. 81-86, XP-009006557, “A Colourmetric Screening Test for Evaluation of the Buffer Capacity of Saliva”, 1980.
S. Wikner, et al., Swedish Dental Journal, vol. 9, No. 2, pp. 45-47, XP-001145508, “A Clinical Evaluation of the Ability of the Dentobuff Method to Estimate Buffer Capacity of Saliva”, 1985.
D. Ericson, et al., Scandinavian Journal of Dental Research, vol. 97, No. 5, pp. 405-407, XP-009006534, “Simplified Method to Estimate Salivary Buffer Capacity”, 1989.
Derwent Publications, AN 1994-035504, XP-002244233, BR 9 301 846, Oct. 26, 1993.
A. Bardow, et al., Archives of Oral Biology, vol. 45, No. 1, pp. 1-12, XP-002244232, “The Buffer Capacity and Buffer Systems of Human Whole Saliva Measured Without Loss of CO2”, Jan. 2002.

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