Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase
Reexamination Certificate
2007-10-09
2007-10-09
Weber, Jon (Department: 1657)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving transferase
Reexamination Certificate
active
10413419
ABSTRACT:
The present invention relates to a novel method to determine CETP activity in a bodily fluid sample wherein the sample may contain an inhibitor of CETP activity. The effect of the inhibitor is preserved to provide a more accurate determination of CETP activity in the fluid. Kits for the practice of the method are also provided.
REFERENCES:
patent: 5512548 (1996-04-01), Kushwaha et al.
patent: 5585235 (1996-12-01), Brocia
patent: 5618683 (1997-04-01), Brocia et al.
patent: 5770355 (1998-06-01), Brocia
patent: 6174693 (2001-01-01), Brocia
patent: 6313142 (2001-11-01), Damon et al.
patent: WO-94/24567 (1994-10-01), None
CARDIOCHEK Microwell ELISA Assays Product Insert accessed Sep. 1, 2005 http:/
lbbs.com/˜alerchek/coronaryArteryDisease.htm.
Bisgaier, C. et al., “Use of Fluorescent Cholesteryl Ester Microemulsions in Cholesteryl Ester Transfer Protein Assays” Journal of Lipid Research 34:1625-1634 (1993).
Dousset, N. and Douste-Blazy, L., “Fluorescent Determination of Cholesteryl Ester Transfer Protein (CETP) Activity in Plasma” Clinical Chemistry 38(2):306 (1982).
Epps, D. et al., “Method for Measuring the Activities of Cholesteryl Ester Transfer Protein (Lipid Transfer Protein)” Chemistry and Physics of Lipids 77:51-63 (1995).
Milner, T. et al., “Enhancement of the Human Plasma Lipid Transfer Protein Reaction by Apolipoproteins” Biochimica Biophysica Acta 1082:71-78 (1991).
Nichols, A. and Smith, L. “Effect of Very Low-Density Lipoproteins on Lipid Transfer in Incubated Serum” Lipid Research 6:206-210 (1965).
Pattnaik, N. et al., “Cholesteryl Ester Exchange Protein in Human Plasma Islolation and Characterization” Biochemica et Biophysica Acta 530:428-438 (1978).
Hayashibe, et al. (1997)Atherosclerosis129:53-58.
Serdyuk, et al. (1999)Arterioscler Thromb Vasc Biol19(3):718-726.
Supplementary European Search Report for EP 03724023.1, mailed on Sep. 8, 2006, 3 pages.
Martin Paul
Morrison & Foerster / LLP
Roar Holding LLC
Weber Jon
LandOfFree
Ex vivo method for determination of CETP activity and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Ex vivo method for determination of CETP activity and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ex vivo method for determination of CETP activity and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3856316