Ex vivo expansion of peripheral blood progenitor cells

Details Ex vivo expansion of peripheral blood progenitor cells Ex vivo expansion of peripheral blood progenitor cells

1993-09-29

1995-12-05

Walsh, Stephen G.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4352403, 424 851, 424 852, 424 855, 424 9371, 4241441, C12N 502, A61K 3514

Patent

active

054728673

ABSTRACT:
Patients suffering from certain types of cancer are treated by high-dose chemotherapy. In order to allow a recovery a process for the ex vivo expansion of peripheral blood progenitor cells is described, wherein CD 34.sup.+ -cells are enriched and cultivated in a medium comprising IL-1, IL-3, IL-6, EPO and SCF. The ex vivo expanded peripheral blood progenitor cells can be administered to cancer patients after chemotherapy.

REFERENCES:
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Brugger et al., Annals of Oncology 65:40a (Oct., 1992).

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