Evolution of whole cells and organisms by recursive sequence...

Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification

Reexamination Certificate

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C435S455000, C435S463000, C435S464000, C800S021000

Reexamination Certificate

active

08076138

ABSTRACT:
The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.

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