Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2005-05-31
2008-07-08
Chin, Christopher L (Department: 1641)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C385S012000, C385S129000, C385S130000, C422S082050, C422S082110, C435S005000, C435S006120, C435S007200, C435S007320, C435S288700, C435S808000, C436S164000, C436S165000, C436S524000, C436S525000, C436S527000, C436S532000, C436S805000
Reexamination Certificate
active
07396676
ABSTRACT:
The invention in particular embodiments provides an evanescent wave sensor which includes a ligand bound to a sensor substrate via a NCYX linker moiety, as defined herein. Methods of making the subject evanescent wave sensors are also provided which include contacting a first reactive moiety which has an isocyanato (or isothiocyanato) moiety with a second reactive moiety which has an hydroxyl, thiol, or amino moiety, as further described herein. Also provided by the invention are methods in which a subject evanescent wave sensor is contacted with a sample, and binding of analytes in the sample to the sensor is assessed by evanescent wave detection. The invention also provides kits and systems for performing the subject methods.
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Robotti Karla M.
Roitman Daniel B.
Agilent Technologie,s Inc.
Chin Christopher L
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