Evaluation of the multidrug resistance phenotype

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...

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424 161, 424 165, 424 181, 424 185, 424 189, 424 9, 436 56, 436 57, 1286531, 1286534, 128654, A61B 505, A61B 600, A61K 4900, G01N 2300

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054076536

ABSTRACT:
The present invention relates to methods for detecting the multidrug resistance phenotype in vivo and in vitro. The invention particularly relates to methods of diagnosing the multidrug resistance phenotype by imaging, particularly scintigraphic imaging, in solid tumors in vivo or in tumors and biopsies in vitro. The methods of the present invention allow the diagnosis of multidrug-resistant tumor and other multidrug-resistant phenotypes without invasive surgical methods.

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