Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1992-04-06
1994-03-22
Saunders, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
424 93V, 424534, 435 724, 435 74, 435 15, 435 29, 436 63, 436 64, 436 86, G01N 33573, G01N 33574
Patent
active
052963535
ABSTRACT:
A method of determining the level of immunosuppression in a mammal involves determining the level of expression of at least one selected TCR subunit protein, or protein in the T lymphocyte signal transduction pathway, and comparing the level to that found in healthy individuals. The method is useful to identify patients having T lymphocytes capable of activation for autologous adoptive immunotherapy and for identifying agents which cause or reverse immunosuppression.
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Loeffler Cynthia M.
Longo Dan L.
Mizoguchi Hiromoto
O'Shea John J.
Ochoa Augusto C.
Regents of the University of Minnesota
Saunders David
The United States of America as represented by the Department of
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