Eutrophic drug compositions based on transferrin glycans

Details Eutrophic drug compositions based on transferrin glycans Eutrophic drug compositions based on transferrin glycans

1998-12-10

2000-04-25

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 23, 514 42, 514 54, A61K 31715, A61K 3813

Patent

active

060544287

ABSTRACT:
The use of transferrin glycans, particularly human transferrin glycans for the production of eutrophic drug compositions is disclosed. These transferrin glycans allow the toxic effects of cytotoxic drugs, e.g., cyclosporin, when used at high dosages or over prolonged times to be alleviated or even suppressed.

REFERENCES:
Genevieve Spik et al., "Comparative study of the primary structure of sero-, lacto-and ovotransferrin glycans from different species", Biochimie, vol. 70 (1988) pp. 1459-1469.

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