Eurcyl, brassidyl and nervonyl derivatives

Details Eurcyl, brassidyl and nervonyl derivatives Eurcyl, brassidyl and nervonyl derivatives

1994-02-28

1995-07-25

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

558169, A61K 31685, C07F 910

Patent

active

054362342

ABSTRACT:
The present invention provides compounds of the formula: ##STR1## wherein R is a erucyl, brassidyl or nervonyl radical, R.sup.1, R.sup.2 and R.sup.3 are defined in the specification, A is a valency bond or a radical as defined in the specification, and X is an oxygen atom when A is a valency bond or is an oxygen or sulphur atom when A is another radical.
The present invention also provides a process for the preparation of the compounds of general formula (I) and pharmaceutical compositions containing them which can be used for the treatment of protozoal and fungal diseases, auto-immune diseases and bone marrow damage.

REFERENCES:
patent: 4542219 (1985-09-01), Hozumi et al.
patent: 4562005 (1985-12-01), Nojima et al.
patent: 5049552 (1991-09-01), Eibl
Kotting et al., Cancer Chemotherapy and Pharmacology, vol. 30, No. 2, 1992, pp. 105-112.

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