Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2011-07-05
2011-07-05
Vogel, Nancy (Department: 1636)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S007100, C435S320100, C530S387100
Reexamination Certificate
active
07972811
ABSTRACT:
The present invention generally relates to methods and compositions for expressing proteins or polypeptides in prokaryotic hosts using eukaryotic signal sequences.
REFERENCES:
patent: 5223409 (1993-06-01), Ladner et al.
patent: 6545140 (2003-04-01), Harmon et al.
patent: 6818411 (2004-11-01), Hutchens et al.
patent: 7094579 (2006-08-01), Gray et al.
patent: 7396661 (2008-07-01), Gray et al.
patent: 2008/0214411 (2008-09-01), Gray et al.
patent: 202 07 301 (2002-05-01), None
patent: 98/47343 (1998-10-01), None
patent: 00/47741 (2000-08-01), None
patent: 03/068956 (2003-08-01), None
de Hostos, E.L., Schilling, J. and Grossman, A.R. Structure and expression of the gene encoding the periplasmic arylsulfatase ofChlamydomonas reinhardtii; Mol. Gen. Genet. vol. 218 (2), pp. 229-239 (1989).
Score Search Results Details for U.S. Appl. No. 12/021,098 and Search Result Oct. 13, 2009 Result 8.
Supplementary European Search Report PCT/US03/04791, Dec. 20, 2005 (5 total pages).
Piers, K.L., Brown, M.H., Hancock, R.E.W., Recombinant DNA procedures for producing small antimicrobial cationic peptides in bacteria, Gene 134 (1992) 7-13.
Haldimann, A., Daniels, L.L., Wanner, B.L., Use of New Methods for Construction of Tightly Regulated Arabinose and Rhamnose Promoter Fusions in Studies of theEscherichia coliPhosphate Regulon, Journal of Bacteriology, Mar. 1998, pp. 1277-1286.
Humphreys, D.P., Sehdev, M., Chapman, A.P., Ganesh, R., Smith, B.J., King, L.M., Glover, D.J., Reeks, D.G., Stephens, P.E., High-Level Periplasmic Expression inEscherichia coliUsing a Eukaryotic Signal Peptide: Importance of Codon Usage at the 5′ End of the Coding Sequence, Protein Expression and Purification 20, pp. 252-264 (2000).
Georigiou, G., et al, Display of heterologous proteins on the surface of microorganisms: From the screening of combininatorial libraries to live recombinant vaccines. Nature Biotechnology, Jan. 1997; 15:29-34.
Jestin et al., “Improving the display of proteins on filamentous phage”, Res. Microbiol 152 (2001) pp. 187-191.
Strobel et al in “Efficient Display of Two Enzymes on Filamentous Phage Using an Improved Signal Sequence” in Molecular Biotechnology, vol. 24, (2003) pp. 1-9.
Fernandez, Luis Angel, “Prokaryotic expression of antibodies and affibodies” in Current Opinion in Biotechnology, Aug. 2004;15:364-373.
Choi and Yee, Secretory and extracellular production of recombinant proteins usingEscherichia coli, Appl Microbiol Biotechnol (2004) 64:625-635.
Nielsen, Henrik, et al., Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites, Protein Engineering (1997) 10(1):1-6.
Pines and Inouye, Expression and Secretion of Proteins inE. coli, Mol Biotech (1999) 12:25-34.
Michaelson, D. et al: Cationic defensins arise from Charge-neutralized propeptides: a mechanism for avoiding leukocyte autocytotoxicity? J Leukoc Biol 51(6):634-639 (1992).
Extended European Search Report, Application No. 08163005.5 EPO Comm dated Feb. 16, 2009.
Buechler Joe
Gray Jeff
Veeramallu Uday Kumar
Hibbert Catherine
Polo John M.
Vogel Nancy
XOMA Technology Ltd.
LandOfFree
Eukaryotic signal sequences for polypeptide expression and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Eukaryotic signal sequences for polypeptide expression and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Eukaryotic signal sequences for polypeptide expression and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2677445