Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-10-03
2006-10-03
Epps-Ford, Janet L. (Department: 1633)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S023100, C536S023700
Reexamination Certificate
active
07115366
ABSTRACT:
The present invention is directed to eubacterial tmDNA sequences and the corresponding tmRNA sequences. The present invention is further directed to alignments of eubacterial tmDNA sequences and the use of the sequences and sequence alignments for the development of antibacterial drugs. The present invention is also directed to the use of the sequences for the development of diagnostic assays.
REFERENCES:
Williams et al. The tmRNA Website. Nucleic Acid Research. 1998, vol. 26, No. 1, pp. 163-165. http:www.wi.mit.edu/bartel/tmRNA/home.
B. Felden et al., “Eubacterial tmRNAs: everywhere except the alpha-Proteobacteria?” Biochimica et Biophysica Acta 1446:145-148, 1999.
N. Nameki et al., “Three of four pseudoknots in tmRNA are interchangeable and are substitutable with single-stranded RNAs,” FEBS Lett 470(3):345-349, Mar. 31, 2000.
N.Nameki et al., “Functional and structural analysis of a pseudoknot upstream of the tag-encoded sequence inE. colitmRNA,” J. Mol. Biol 286(3):733-744, Feb. 26, 1999.
W. Schönhuber et al., “Utilization of tmRNA squences for bacterial identification,” MBC Microbiology 2001, 1:20 (online, 8 pages).
K.P. Williams et al., “Phylogenetic analysis of tmRNA secondary structure,” RNA 2:1306-1310, 1996.
C. Zwieb et al., “Survey and Summary, Comparative sequence analysis of tmRNA,” Nucleic Acids Research 27(10):2063-2071, 1999.
Epps-Ford Janet L.
Rothwell Figg Ernst & Manbeck
University of Utah Research Foundation
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