Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1986-04-02
1987-12-15
Griffin, Ronald W.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424456, 514 27, 514 33, 536 181, 549298, C07H 1520, C07H 1524, C07D31744, A61K 942
Patent
active
047132469
ABSTRACT:
A liquid dosage form suitable for oral administration of etoposide which is sufficiently concentrated to be administered in capsule form and which provides improved absorption of the drug relative to prior oral formulations.
REFERENCES:
patent: 3408441 (1968-10-01), Wartburg et al.
patent: 3524844 (1970-08-01), Keller-Juslen et al.
patent: 4567253 (1986-01-01), Durst et al.
Falkson et al, Cancer, Apr. 1975, vol. 35(4), pp. 1141-1144.
D'Incalci et al., Pharmacokinetics of VP16-213, Given by Different Administration Methods, Chem. Abstracts 97:275w, (1982).
Westergaard et al., The Mechanism Whereby Bile Acid Micelles Increase the Rate of Fatty Acid and Cholesterol Uptake into the Intestinal Mucosal Cell, Chem. Abstracts 85:75523m, (1976).
Bates et al., Solubilizing Properties of Bile Salt Solutions . . . on . . . Glutethimide, Griseofulvin, and Hexestrol, Chem. Abstracts 64:9517e (1966), 65:15165a (1966).
Bates et al., Rates of Dissolution of Griseofulvin and Hexestrol in Bile Salt Solutions, Chem. Abstracts 65:8680b, (1966).
Malone et al., Deoxycholic Acid Enhancement of Orally Administered Reserpine, Chem. Abstracts 65:14303e, (1966).
NCI Investigational Drugs--Phar. Data, 1981, pp. 117-119, NIH Publication No. 81-2141.
Cancer Chemotherapy and Pharmacology, (1982), 7:141-145.
Jour. of Pharm. Sciences, (Bates et al.), 55, 191-199, (1966).
Jour. of Pharm. Sciences, (Malone et al.), 55, 972-974, (1966).
Jour. of Clinical Investigation, (Westergaard et al.), 58, 97-108, (1976).
Begum Selima
Nunning Bernard C.
Ullah Ismat
Bristol-Myers Company
Griffin Ronald W.
Johnson Lester E.
LandOfFree
Etoposide oral dosage form does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Etoposide oral dosage form, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Etoposide oral dosage form will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1219142